Genomics in Wolfram|Alpha
When we were building the initial version of Wolfram|Alpha, one of my first challenges was to extend the genome search engine I wrote for the Wolfram Language so it could return results in Wolfram|Alpha:
Along with genome searches, I built a database of genes so Wolfram|Alpha users could drill down on specific genes matching the query sequence. For a given gene you can see the chromosome location:
... nearby genes:
... and gene homologs in other species:
... among other things.
We also allowed users to see the physical properties of the query sequences, in particular the melting temperature and its dependence on salt concentration: